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| thuis | Uit | Datum | Uitslag |
| VVV-Venlo | PSV | 17 mrt 2019 | 0-1 (0-0) |
| AZ | Ajax | 17 mrt 2019 | 1-0 (0-0) |
| FC Groningen | ADO Den Haag | 17 mrt 2019 | 1-0 (1-0) |
| Excelsior | PEC Zwolle | 17 mrt 2019 | 0-2 (0-0) |
| sc Heerenveen | De Graafschap | 16 mrt 2019 | 0-3 (0-1) |
| Feyenoord | Willem II | 16 mrt 2019 | 2-3 (1-1) |
| NAC Breda | FC Utrecht | 16 mrt 2019 | 0-4 (0-2) |
| Heracles Almelo | Vitesse | 16 mrt 2019 | 3-2 (2-2) |
| Fortuna Sittard | FC Emmen | 15 mrt 2019 | 3-1 (3-0) |
| Ajax | PEC Zwolle | 13 mrt 2019 | 2-1 (1-0) |
Last updated: 22 March 2019 - 07:40.58
| Gespeeld | Gewonnen | Gelijk | Verloren | Punten | +/- | ||
| 1 | PSV | 26 | 21 | 4 | 1 | 67 | 79 - 16 |
| 2 | Ajax | 26 | 20 | 2 | 4 | 62 | 88 - 22 |
| 3 | Feyenoord | 26 | 14 | 5 | 7 | 47 | 55 - 33 |
| 4 | AZ | 26 | 14 | 5 | 7 | 47 | 52 - 30 |
| 5 | Vitesse | 26 | 11 | 7 | 8 | 40 | 47 - 36 |
| 6 | FC Utrecht | 26 | 11 | 7 | 8 | 40 | 45 - 34 |
| 7 | Heracles Almelo | 26 | 12 | 3 | 11 | 39 | 46 - 50 |
| 8 | FC Groningen | 26 | 10 | 5 | 11 | 35 | 31 - 34 |
| 9 | Willem II | 26 | 10 | 4 | 12 | 34 | 43 - 50 |
| 10 | Sc Heerenveen | 26 | 8 | 9 | 9 | 33 | 56 - 59 |
| 11 | VVV-Venlo | 26 | 9 | 5 | 12 | 32 | 32 - 44 |
| 12 | PEC Zwolle | 26 | 8 | 5 | 13 | 29 | 30 - 41 |
| 13 | Fortuna Sittard | 26 | 8 | 5 | 13 | 29 | 43 - 61 |
| 14 | ADO Den Haag | 26 | 7 | 7 | 12 | 28 | 35 - 52 |
| 15 | Excelsior | 26 | 7 | 5 | 14 | 26 | 32 - 59 |
| 16 | De Graafschap | 26 | 7 | 4 | 15 | 25 | 31 - 55 |
| 17 | FC Emmen | 26 | 6 | 7 | 13 | 25 | 30 - 60 |
| 18 | NAC Breda | 26 | 4 | 5 | 17 | 17 | 23 - 62 |
Last updated: 22 March 2019 - 07:40.58
| Thuis | Uit | Datum | Tijd | |
| ADO Den Haag | Vitesse | 30 mrt 2019 | 18.30 | |
| Willem II | Fortuna Sittard | 30 mrt 2019 | 18.30 | |
| De Graafschap | Heracles Almelo | 30 mrt 2019 | 19.45 | |
| AZ | FC Groningen | 30 mrt 2019 | 20.45 | |
| Sc Heerenveen | Excelsior | 30 mrt 2019 | 20.45 | |
| NAC Breda | VVV-Venlo | 31 mrt 2019 | 12.15 | |
| FC Utrecht | Feyenoord | 31 mrt 2019 | 14.30 | |
| PEC Zwolle | FC Emmen | 31 mrt 2019 | 14.30 | |
| Ajax | PSV | 31 mrt 2019 | 16.45 |
Last updated: 22 March 2019 - 07:40.58
| Date | Time | Match | Result |
| 11 Aug 2018 | 20:45 hrs | PSV - FC Utrecht | 4 - 0 |
| 18 Aug 2018 | 20:45 hrs | Fortuna Sittard - PSV | 1 - 2 |
| 25 Aug 2018 | 20:45 hrs | PEC Zwolle - PSV | 1 - 2 |
| 1 Sep 2018 | 19:45 hrs | PSV - Willem II | 6 - 1 |
| 15 Sep 2018 | 18:30 hrs | ADO Den Haag - PSV | 0 - 7 |
| 23 Sep 2018 | 16:45 hrs | PSV - Ajax | 3 - 0 |
| 29 Sep 2018 | 18:30 hrs | NAC Breda - PSV | 0 - 2 |
| 6 Oct 2018 | 19:45 hrs | PSV - VVV-Venlo | 4 - 0 |
| 20 Oct 2018 | 18:30 hrs | PSV - FC Emmen | 6 - 0 |
| 27 Oct 2018 | 19:45 hrs | FC Groningen - PSV | 1 - 2 |
| 3 Nov 2018 | 18:30 hrs | PSV - Vitesse | 1 - 0 |
| 10 Nov 2018 | 19:45 hrs | De Graafschap - PSV | 1 - 4 |
| 24 Nov 2018 | 20:45 hrs | PSV - sc Heerenveen | 3 - 0 |
| 2 Dec 2018 | 14:30 hrs | Feyenoord - PSV | 2 - 1 |
| 7 Dec 2018 | 20:45 hrs | PSV - Excelsior | 6 - 0 |
| 15 Dec 2018 | 19:45 hrs | Heracles Almelo - PSV | 0 - 4 |
| 22 Dec 2018 | 19:45 hrs | PSV - AZ | 3 - 1 |
| 20 Jan 2019 | 14:30 hrs | FC Emmen - PSV | 2 - 2 |
| 26 Jan 2019 | 19:45 hrs | PSV - FC Groningen | 2 - 1 |
| 3 Feb 2019 | 14:30 hrs | PSV - Fortuna Sittard | 5 - 0 |
| 10 Feb 2019 | 16:45 hrs | FC Utrecht - PSV | 2 - 2 |
| 16 Feb 2019 | 19:45 hrs | sc Heerenveen - PSV | 2 - 2 |
| 24 Feb 2019 | 14:30 hrs | PSV - Feyenoord | 1 - 1 |
| 2 Mar 2019 | 19:45 hrs | Excelsior - PSV | 0 - 2 |
| 9 Mar 2019 | 19:45 hrs | PSV - NAC Breda | 2 - 0 |
| 17 Mar 2019 | 12:15 hrs | VVV-Venlo - PSV | 0 - 1 |
| 31 Mar 2019 | 16:45 hrs | Ajax - PSV | |
| 4 Apr 2019 | 18:30 hrs | PSV - PEC Zwolle | |
| 7 Apr 2019 | 16:45 hrs | Vitesse - PSV | |
| 14 Apr 2019 | 12:15 hrs | PSV - De Graafschap | |
| 21 Apr 2019 | 16:45 hrs | PSV - ADO Den Haag | |
| 25 Apr 2019 | 20:45 hrs | Willem II - PSV | |
| 28 Apr 2019 | 14:30 hrs | PSV - Heracles Almelo | |
| 12 May 2019 | 14:30 hrs | AZ - PSV |