| # | Team | GespeeldWed. | GewonnenWinst | GelijkGelijk | VerlorenVerl. | Punten | Doelsaldo |
| 1 | Feyenoord | 25 | 17 | 7 | 1 | 58 | 56 - 23 |
| 2 | Ajax | 25 | 16 | 7 | 2 | 55 | 70 - 25 |
| 3 | AZ | 25 | 16 | 5 | 4 | 53 | 51 - 28 |
| 4 | PSV | 25 | 16 | 4 | 5 | 52 | 66 - 30 |
| 5 | FC Twente | 25 | 12 | 8 | 5 | 44 | 42 - 21 |
| 6 | Sparta Rotterdam | 25 | 12 | 7 | 6 | 43 | 39 - 27 |
| 7 | FC Utrecht | 25 | 10 | 8 | 7 | 38 | 41 - 39 |
| 8 | RKC Waalwijk | 24 | 8 | 8 | 8 | 32 | 39 - 37 |
| 9 | NEC | 25 | 6 | 13 | 6 | 31 | 32 - 25 |
| 10 | Sc Heerenveen | 25 | 8 | 7 | 10 | 31 | 29 - 36 |
| 11 | Fortuna Sittard | 25 | 8 | 5 | 12 | 29 | 31 - 44 |
| 12 | Go Ahead Eagles | 24 | 6 | 8 | 10 | 26 | 34 - 43 |
| 13 | Vitesse | 25 | 5 | 8 | 12 | 23 | 29 - 45 |
| 14 | FC Volendam | 25 | 6 | 5 | 14 | 23 | 29 - 55 |
| 15 | FC Emmen | 25 | 4 | 9 | 12 | 21 | 23 - 43 |
| 16 | Excelsior | 25 | 6 | 2 | 17 | 20 | 21 - 60 |
| 17 | FC Groningen | 25 | 4 | 5 | 16 | 17 | 25 - 50 |
| 18 | SC Cambuur | 25 | 4 | 4 | 17 | 16 | 19 - 45 |
Last updated: 17 March 2023 - 19:04.00
| Date | Time | Match | Result |
| 6 Aug 2022 | 20:00 hrs | PSV - FC Emmen | 4 - 1 |
| 13 Aug 2022 | 18:45 hrs | Go Ahead Eagles - PSV | 2 - 5 |
| 28 Aug 2022 | 14:30 hrs | Excelsior - PSV | 1 - 6 |
| 31 Aug 2022 | 18:45 hrs | PSV - FC Volendam | 7 - 1 |
| 3 Sep 2022 | 18:45 hrs | FC Twente - PSV | 2 - 1 |
| 11 Sep 2022 | 14:30 hrs | PSV - RKC Waalwijk | 1 - 0 |
| 18 Sep 2022 | 14:30 hrs | PSV - Feyenoord | 4 - 3 |
| 1 Oct 2022 | 16:30 hrs | SC Cambuur - PSV | 3 - 0 |
| 9 Oct 2022 | 16:45 hrs | SC Heerenveen - PSV | 0 - 1 |
| 16 Oct 2022 | 14:30 hrs | PSV - FC Utrecht | 6 - 1 |
| 23 Oct 2022 | 14:30 hrs | FC Groningen - PSV | 4 - 2 |
| 30 Oct 2022 | 14:30 hrs | PSV - NEC | 3 - 0 |
| 6 Nov 2022 | 16:45 hrs | Ajax - PSV | 1 - 2 |
| 12 Nov 2022 | 21:00 hrs | PSV - AZ | 0 - 1 |
| 7 Jan 2023 | 21:00 hrs | PSV - Sparta Rotterdam | 0 - 0 |
| 15 Jan 2023 | 14:30 hrs | Fortuna Sittard - PSV | 2 - 2 |
| 21 Jan 2023 | 20:00 hrs | PSV - Vitesse | 1 - 0 |
| 24 Jan 2023 | 18:45 hrs | FC Emmen - PSV | 1 - 0 |
| 28 Jan 2023 | 16:30 hrs | PSV - Go Ahead Eagles | 2 - 0 |
| 5 Feb 2023 | 14:30 hrs | Feyenoord - PSV | 2 - 2 |
| 11 Feb 2023 | 20:00 hrs | PSV - FC Groningen | 6 - 0 |
| 19 Feb 2023 | 14:30 hrs | FC Utrecht - PSV | 2 - 2 |
| 26 Feb 2023 | 16:45 hrs | PSV - FC Twente | 3 - 1 |
| 5 Mar 2023 | 14:30 hrs | RKC Waalwijk - PSV | 0 - 1 |
| 12 Mar 2023 | 16:45 hrs | PSV - SC Cambuur | 5 - 2 |
| 19 Mar 2023 | 16:45 hrs | Vitesse - PSV | |
| 1 Apr 2023 | 20:00 hrs | NEC - PSV | |
| 8 Apr 2023 | 20:00 hrs | PSV - Excelsior | |
| 16 Apr 2023 | 16:45 hrs | FC Volendam - PSV | |
| 23 Apr 2023 | 14:30 hrs | PSV - Ajax | |
| 6 May 2023 | 18:45 hrs | Sparta Rotterdam - PSV | |
| 14 May 2023 | 20:00 hrs | PSV - Fortuna Sittard | |
| 21 May 2023 | 14:30 hrs | PSV - SC Heerenveen | |
| 28 May 2023 | 14:30 hrs | AZ - PSV |
