| # | Team | GespeeldWed. | GewonnenWinst | GelijkGelijk | VerlorenVerl. | Punten | Doelsaldo |
| 1 | PSV | 16 | 14 | 1 | 1 | 43 | 50 - 20 |
| 2 | Feyenoord | 16 | 11 | 1 | 4 | 34 | 41 - 20 |
| 3 | Ajax | 16 | 8 | 5 | 3 | 29 | 30 - 20 |
| 4 | N.E.C. | 16 | 8 | 4 | 4 | 28 | 41 - 27 |
| 5 | FC Groningen | 16 | 8 | 2 | 6 | 26 | 24 - 21 |
| 6 | AZ | 15 | 7 | 4 | 4 | 25 | 28 - 24 |
| 7 | FC Twente | 16 | 6 | 6 | 4 | 24 | 25 - 20 |
| 8 | FC Utrecht | 16 | 6 | 5 | 5 | 23 | 27 - 21 |
| 9 | Sc Heerenveen | 16 | 5 | 5 | 6 | 20 | 26 - 26 |
| 10 | Sparta Rotterdam | 16 | 6 | 2 | 8 | 20 | 17 - 31 |
| 11 | PEC Zwolle | 16 | 5 | 4 | 7 | 19 | 20 - 36 |
| 12 | Go Ahead Eagles | 16 | 4 | 6 | 6 | 18 | 25 - 28 |
| 13 | Fortuna Sittard | 16 | 5 | 3 | 8 | 18 | 21 - 26 |
| 14 | Excelsior | 15 | 5 | 1 | 9 | 16 | 14 - 26 |
| 15 | FC Volendam | 16 | 3 | 5 | 8 | 14 | 19 - 30 |
| 16 | Heracles Almelo | 16 | 4 | 2 | 10 | 14 | 26 - 41 |
| 17 | NAC Breda | 16 | 3 | 4 | 9 | 13 | 16 - 25 |
| 18 | Telstar | 16 | 2 | 6 | 8 | 12 | 19 - 27 |
| Dag | Date | Time | Match | Result |
| sa | 9 Aug 2025 | 21:00 hrs | PSV - Sparta Rotterdam | 6 - 1 |
| su | 17 Aug 2025 | 14:30 hrs | FC Twente - PSV | 0 - 2 |
| sa | 23 Aug 2025 | 18:45 hrs | PSV - FC Groningen | 4 - 2 |
| sa | 30 Aug 2025 | 20:00 hrs | PSV - Telstar | 0 - 2 |
| sa | 13 Sep 2025 | 18:45 hrs | N.E.C. - PSV | 3 - 5 |
| su | 21 Sep 2025 | 14:30 hrs | PSV - Ajax | 2 - 2 |
| sa | 27 Sep 2025 | 20:00 hrs | Excelsior Rotterdam - PSV | 1 - 2 |
| sa | 4 Oct 2025 | 20:00 hrs | PEC Zwolle - PSV | 0 - 4 |
| sa | 18 Oct 2025 | 18:45 hrs | PSV - Go Ahead Eagles | 2 - 1 |
| su | 26 Oct 2025 | 14:30 hrs | Feyenoord - PSV | 2 - 3 |
| fr | 31 Oct 2025 | 20:00 hrs | PSV - Fortuna Sittard | 5 - 2 |
| su | 9 Nov 2025 | 16:45 hrs | AZ - PSV | 1 - 5 |
| sa | 22 Nov 2025 | 16:30 hrs | NAC Breda - PSV | 0 - 1 |
| su | 30 Nov 2025 | 12:15 hrs | PSV - FC Volendam | 3 - 0 |
| sa | 6 Dec 2025 | 16:30 hrs | sc Heerenveen - PSV | 0 - 2 |
| sa | 13 Dec 2025 | 20:00 hrs | PSV - Heracles Almelo | 4 - 3 |
| su | 21 Dec 2025 | 12:15 hrs | FC Utrecht - PSV | |
| sa | 10 Jan 2026 | 20:00 hrs | PSV - Excelsior Rotterdam | |
| sa | 17 Jan 2026 | 20:00 hrs | Fortuna Sittard - PSV | |
| sa | 24 Jan 2026 | 20:00 hrs | PSV - NAC Breda | |
| su | 1 Feb 2026 | 14:30 hrs | PSV - Feyenoord | |
| su | 10 May 2026 | 16:45 hrs | Go Ahead Eagles - PSV | |
| su | 17 May 2026 | 14:30 hrs | PSV - FC Twente |