| # | Team | GespeeldWed. | GewonnenWinst | GelijkGelijk | VerlorenVerl. | Punten | Doelsaldo |
| 1 | PSV | 12 | 10 | 1 | 1 | 31 | 40 - 17 |
| 2 | Feyenoord | 12 | 9 | 1 | 2 | 28 | 31 - 12 |
| 3 | AZ | 12 | 7 | 3 | 2 | 24 | 25 - 18 |
| 4 | Ajax | 12 | 5 | 5 | 2 | 20 | 22 - 17 |
| 5 | FC Utrecht | 12 | 6 | 1 | 5 | 19 | 22 - 16 |
| 6 | FC Groningen | 12 | 6 | 1 | 5 | 19 | 17 - 17 |
| 7 | N.E.C. | 12 | 5 | 3 | 4 | 18 | 29 - 20 |
| 8 | FC Twente | 12 | 4 | 4 | 4 | 16 | 20 - 18 |
| 9 | Go Ahead Eagles | 12 | 4 | 4 | 4 | 16 | 19 - 18 |
| 10 | Fortuna Sittard | 12 | 5 | 1 | 6 | 16 | 18 - 20 |
| 11 | Sparta Rotterdam | 12 | 5 | 1 | 6 | 16 | 14 - 24 |
| 12 | Sc Heerenveen | 12 | 3 | 5 | 4 | 14 | 19 - 21 |
| 13 | FC Volendam | 12 | 3 | 4 | 5 | 13 | 16 - 20 |
| 14 | NAC Breda | 12 | 3 | 3 | 6 | 12 | 15 - 21 |
| 15 | PEC Zwolle | 12 | 3 | 3 | 6 | 12 | 14 - 27 |
| 16 | Excelsior | 12 | 3 | 1 | 8 | 10 | 11 - 23 |
| 17 | Telstar | 12 | 2 | 3 | 7 | 9 | 14 - 21 |
| 18 | Heracles Almelo | 12 | 3 | 0 | 9 | 9 | 17 - 33 |
| Dag | Date | Time | Match | Result |
| sa | 9 Aug 2025 | 21:00 hrs | PSV - Sparta Rotterdam | 6 - 1 |
| su | 17 Aug 2025 | 14:30 hrs | FC Twente - PSV | 0 - 2 |
| sa | 23 Aug 2025 | 18:45 hrs | PSV - FC Groningen | 4 - 2 |
| sa | 30 Aug 2025 | 20:00 hrs | PSV - Telstar | 0 - 2 |
| sa | 13 Sep 2025 | 18:45 hrs | N.E.C. - PSV | 3 - 5 |
| su | 21 Sep 2025 | 14:30 hrs | PSV - Ajax | 2 - 2 |
| sa | 27 Sep 2025 | 20:00 hrs | Excelsior Rotterdam - PSV | 1 - 2 |
| sa | 4 Oct 2025 | 20:00 hrs | PEC Zwolle - PSV | 0 - 4 |
| sa | 18 Oct 2025 | 18:45 hrs | PSV - Go Ahead Eagles | 2 - 1 |
| su | 26 Oct 2025 | 14:30 hrs | Feyenoord - PSV | 2 - 3 |
| fr | 31 Oct 2025 | 20:00 hrs | PSV - Fortuna Sittard | 5 - 2 |
| su | 9 Nov 2025 | 16:45 hrs | AZ - PSV | 1 - 5 |
| sa | 22 Nov 2025 | 16:30 hrs | NAC Breda - PSV | |
| su | 30 Nov 2025 | 12:15 hrs | PSV - FC Volendam | |
| sa | 6 Dec 2025 | 16:30 hrs | sc Heerenveen - PSV | |
| sa | 13 Dec 2025 | 20:00 hrs | PSV - Heracles Almelo | |
| su | 21 Dec 2025 | 12:15 hrs | FC Utrecht - PSV | |
| sa | 10 Jan 2026 | 20:00 hrs | PSV - Excelsior Rotterdam | |
| sa | 17 Jan 2026 | 20:00 hrs | Fortuna Sittard - PSV | |
| sa | 24 Jan 2026 | 20:00 hrs | PSV - NAC Breda | |
| su | 1 Feb 2026 | 14:30 hrs | PSV - Feyenoord | |
| su | 10 May 2026 | 16:45 hrs | Go Ahead Eagles - PSV | |
| su | 17 May 2026 | 14:30 hrs | PSV - FC Twente |